19 February 2026
Chicago 12, Melborne City, USA
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Pima County Sheriff pleads for Nancy Guthrie’s release as reward for help spikes

The Pima County Sheriff’s Office said in a press release Wednesday that investigators are “currently analyzing biological evidence found at Nancy Guthrie’s residence.” 

DNA profiles found at the home and on a glove discovered roughly two miles from Guthrie’s address are currently undergoing genetic genealogy testing after the samples failed to reach a match in law enforcement’s CODIS database. 

However, biological evidence and DNA are not necessarily the same and can be treated differently by investigators. 

“Biological evidence is the raw material collected at a scene, things like blood, hair, saliva and skin cells,” retired FBI agent Jason Pack told Fox News Digital. “DNA is what investigators hope to extract from that material after lab processing, and that process is not automatic or guaranteed.” 

Pack added the process can become even more complicated if a singular piece of evidence contains biological material from more than one individual. 

“Investigators then have to work to isolate and separate those individual profiles before any comparison can even be attempted,” Pack said. “That is a painstaking process that adds significant time to the analysis.” 

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